![]() 17 Numerous factors appear to be involved, but overall, susceptibility remains poorly understood.Īlthough there still is no good proven cure for the common cold, a number of treatments have been reported to have symptom-reducing benefit in one or more randomized controlled trials (RCTs). 14, 15, 16 Some individuals are particularly prone to colds, whereas others get them infrequently. ![]() For adults, the average is two to three symptomatic colds per year and perhaps one or two asymptomatic infections. On average, children experience four to six symptomatic colds per year, in addition to several asymptomatic infections. 8, 9, 10Īlthough colds are often considered a nuisance rather than a major public health threat, even rhinovirus, the least pathogenic of the common cold viruses, may cause death among elderly and immunocompromised individuals. 5, 6, 7 Influenza causes an annual mid-winter epidemic that varies year to year, but can be a major cause of hospitalization and death. ![]() In the United States, noninfluenza ARI accounts for more than 20 million clinic visits and 40 million lost days of school and work, with total costs estimated at $40 billion, making noninfluenza ARI the seventh most expensive illness. 1, 2, 3, 4 Acute respiratory infections (ARIs) are often classified as being caused either by influenza, the most serious of the common viruses, or other viruses (noninfluenza ARI). ![]() Humanity’s most frequent illness, the common cold, is caused by acute viral infection of the upper respiratory tract. ![]()
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